(RS)-3-AMINO-2-(4-CHLOROPHENYL)PROPYLSULFONIC ACID
SACLOFEN
CAS: 125464-42-8
Molecular Formula: C9H12ClNO3S
(RS)-3-AMINO-2-(4-CHLOROPHENYL)PROPYLSULFONIC ACID - Names and Identifiers
| Name | SACLOFEN |
| Synonyms | SACLOFEN SACLOFEN SELECTIVE GABA(B) REC 3-AMINO-2-(4-CHLOROPHENYL)-PROPANE SULFONIC ACID 3-AMino-2-(4-chlorophenyl)propane-1-sulfonic acid (RS)-3-amino-2-(4-chlorophenyl)propylsulfonic acid β-(aminomethyl)-4-chlorobenzeneethanesulfonic acid (RS)-3-AMINO-2-(4-CHLOROPHENYL)PROPYLSULFONIC ACID BETA-(AMINOMETHYL)-4-CHLOROBENZENEETHANESULFONIC ACID BETA-(AMINOMETHYL)-4-CHLORO-BENZENEETHANESULPHONIC ACID |
| CAS | 125464-42-8 |
| InChI | InChI=1/C9H12ClNO3S/c10-9-3-1-7(2-4-9)8(5-11)6-15(12,13)14/h1-4,8H,5-6,11H2,(H,12,13,14) |
| InChIKey | JYLNVJYYQQXNEK-UHFFFAOYSA-N |
(RS)-3-AMINO-2-(4-CHLOROPHENYL)PROPYLSULFONIC ACID - Physico-chemical Properties
| Molecular Formula | C9H12ClNO3S |
| Molar Mass | 249.71 |
| Density | 1.437±0.06 g/cm3(Predicted) |
| Melting Point | 310-315℃ (decomposition) |
| Solubility | 0.1 M NaOH: 20mg/mL |
| Appearance | solid |
| Color | white |
| pKa | 1.15±0.50(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.6 |
| Physical and Chemical Properties | Solubility: 0.1 M NaOH: 20 mg/mL WGK Germany:3 |
(RS)-3-AMINO-2-(4-CHLOROPHENYL)PROPYLSULFONIC ACID - Risk and Safety
| WGK Germany | 3 |
(RS)-3-AMINO-2-(4-CHLOROPHENYL)PROPYLSULFONIC ACID - Introduction
3-Amino -2-(4-chlorophenyl)-propanesulfonic acid (abbreviated as ACPA) is an organic compound. It has a chemical formula of C9H12ClNO3S and a molecular weight of about 239.71g/mol.
ACPA is a solid, usually white crystalline powder. It is stable at room temperature, but may decompose at high temperatures or under the action of strong acids. ACPA has a high solubility in water and a relatively low solubility in organic solvents.
ACPA has pharmaceutical activity and is widely used as a pharmaceutical intermediate. It is a non-guanine PPARγ agonist and is used in the field of diabetes treatment. In addition, ACPA can also be used to synthesize other drugs, such as anti-tumor drugs and anti-inflammatory drugs.
The preparation of ACPA is usually achieved by chemical synthesis. A common synthetic method is to react 4-chloroacetophenone with sulfuric acid and an oxidizing agent to produce 3-amino -2-(4-chlorophenyl)-propenone, which is then reacted with threesulfonic acid to form ACPA.
Some safety information needs to be paid attention to when using and handling ACPA. It is irritating and may cause irritation to the eyes, skin and respiratory tract. Therefore, it is necessary to wear appropriate personal protective equipment, such as safety glasses, gloves and respiratory protection equipment. At the same time, it should be used in a well-ventilated laboratory environment and avoid contact with strong acids and strong oxidants to avoid dangerous reactions.
In summary, 3-amino -2-(4-chlorophenyl)-propanesulfonic acid is an organic compound with pharmaceutical activity and has important applications in the fields of drug synthesis and diabetes treatment. However, safety precautions should be paid attention to when using and handling.
ACPA is a solid, usually white crystalline powder. It is stable at room temperature, but may decompose at high temperatures or under the action of strong acids. ACPA has a high solubility in water and a relatively low solubility in organic solvents.
ACPA has pharmaceutical activity and is widely used as a pharmaceutical intermediate. It is a non-guanine PPARγ agonist and is used in the field of diabetes treatment. In addition, ACPA can also be used to synthesize other drugs, such as anti-tumor drugs and anti-inflammatory drugs.
The preparation of ACPA is usually achieved by chemical synthesis. A common synthetic method is to react 4-chloroacetophenone with sulfuric acid and an oxidizing agent to produce 3-amino -2-(4-chlorophenyl)-propenone, which is then reacted with threesulfonic acid to form ACPA.
Some safety information needs to be paid attention to when using and handling ACPA. It is irritating and may cause irritation to the eyes, skin and respiratory tract. Therefore, it is necessary to wear appropriate personal protective equipment, such as safety glasses, gloves and respiratory protection equipment. At the same time, it should be used in a well-ventilated laboratory environment and avoid contact with strong acids and strong oxidants to avoid dangerous reactions.
In summary, 3-amino -2-(4-chlorophenyl)-propanesulfonic acid is an organic compound with pharmaceutical activity and has important applications in the fields of drug synthesis and diabetes treatment. However, safety precautions should be paid attention to when using and handling.
Last Update：2024-04-09 21:11:58
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CAS: 125464-42-8
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Mobile: 18021002903
QQ: 3008007409
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